PredniSONE FAQ

What is Prednisone?

This is a artificial form of corticosteroid and, when introduced into the body, adds to and eventually replaces cortisol, a steroid hormone produced in your adrenal gland.

What does it do?

Prednisone is mainly an anti-inflammatory drug but, in combination with anticancer drugs, it also controls the growth of some tumors. Finally, because it affects the way the immune system works, it’s used to prevent the rejection of transplanted organs.

What are the problems?

There are three key problems with the use of this drug. First, if you take it for more than seven days, it quickly shuts down the operation of your adrenal gland. This means you almost immediately become physically dependent on taking this drug and cannot stop taking it suddenly. To give your adrenal gland the chance to start working again, you must taper the dose until the gland resumes the natural production of cortisol. Second, you will need to adjust the dosage if your stress levels rise significantly. Third, it weakens your immune system and makes you more likely to catch any disease or illness from those you meet. If you know someone is ill, do not visit with them. If a member of your household fall ill, avoid them. Some diseases may become fatal if your immune system does not fight the infection.

What is the dosage?

For use in the home, you will be given a tablet. It’s important to follow the directions given both when starting and stopping the course of treatment. Prednisone is also available in a liquid form which you measure out with a special spoon or cup. Do not guess how much to take. In hospital, Prednisone can be given as an injection or through the use of an IV drip.

What are the possible side effects?

The use of all steroids over time can be problematic and Prednisone is no exception. At the lower end of the scale, you may find you suffer headaches and some dizziness. There can also be a redistribution of the fat around your body, a slowing in the rate at which you heal if bruised or cut, and a thinning of the skin. Mostly, these effects will recede after you stop taking the drug, but it can be a slow process. However, there are some more serious side effects. Some people gain weight rapidly and have gastric problems with stomach pain, nausea and vomiting. There can be dangerously high blood pressure, chest pain and difficulty breathing. Finally, some become very confused and depressed. If you are affected by any of these latter symptoms, seek emergency medical attention.